RNA Interference: A New Tool for Genetic Analysis and Therapeutics

Dr. Stephane Kissler, MIT OpenCourseWare

This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting.
To understand and treat any disease with a genetic basis or predisposition, scientists and clinicians need effective ways of manipulating the levels of genes and gene products. Conventional methods for the genetic modification of many experimental organisms are technically demanding and time consuming. Just over 5 years ago, a new mechanism of gene-silencing, termed RNA interference (RNAi), was discovered. In addition to being a fascinating biological process, RNAi provides a revolutionary technology that has already changed the way biomedical research is done and that may even prove useful for genetic interventions in a clinical context. In this course, students learn how RNAi was discovered, how it works, and what its physiological relevance might be. How RNAi can be harnessed to modulate gene expression and perform genetic screens, both in cells and in various organisms is also covered. Finally, this course examines the first attempts to use RNAi for the treatment of models of human diseases in experimental animals.

Dates:
  • Free schedule
Course properties:
  • Free:
  • Paid:
  • Certificate:
  • MOOC:
  • Video:
  • Audio:
  • Email-course:
  • Language: English Gb

Reviews

No reviews yet. Want to be the first?

Register to leave a review

Show?id=n3eliycplgk&bids=695438
NVIDIA
More on this topic:
7-349s11 Stem Cells: A Cure or Disease?
Have you ever considered going to a pharmacy to order some new cardiomyocytes...
7-342f11 The Biology of Aging: Age-Related Diseases and Interventions
Aging involves an intrinsic and progressive decline in function that eventually...
7-013s06 Introductory Biology (Spring 2006)
The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover...
7-013s13 Introductory Biology (Spring 2013)
The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover...
7-60s10 Cell Biology: Structure and Functions of the Nucleus
The goal of this course is to teach both the fundamentals of nuclear cell biology...
More from 'Biology & Life Sciences':
Title Course in Science Journalism
Welcome to the world’s first online course in science journalism, developed...
Ctga16 Current Topics in Genome Analysis 2016
A lecture series covering contemporary areas in genomics and bioinformatics...
Ctga Current Topics in Genome Analysis 2014
A lecture series covering contemporary areas in genomics and bioinformatics...
Yali-friedman Biotechnology
As biotechnology changes paradigms in medicine, agriculture, and industrial...
Virology_coursera Virology
This Columbia University virology course is offered each year in the spring...
More from 'MIT OpenCourseWare':
1-00s12 Introduction to Computers and Engineering Problem Solving
This course presents the fundamentals of object-oriented software design and...
1-010f08 Uncertainty in Engineering
This course gives an introduction to probability and statistics, with emphasis...
1-011s11 Project Evaluation
1.011 Project Evaluation covers methodologies for evaluating civil engineering...
1-012s02 Introduction to Civil Engineering Design
1.012 introduces students to the theory, tools, and techniques of engineering...
1-017f03 Computing and Data Analysis for Environmental Applications
This subject is a computer-oriented introduction to probability and data analysis...

© 2013-2019